Michael Muller was born in Gunzburg at the Donau. He studied cello at the Musikhochschule Muenchen and the Universitaet der Kuenste in Berlin, Participating in masterclasses with Boris Pergamenschikof, David Geringas and Heinrich Schiff.
From 1987 till 1995 he was solocellist of the Deutsche Kammerphilharmonie Bremen. Between 1995 and 2013 he was solocellist of the Radio Kamerorkest resp. Radio Kamerfilharmonie.
In 2013 he became solocellist of the Radio Filharmonisch Orkest. He trained as a chambermusician with Walter Levin (Lasalle Quartet),Amadeus Quartet in Cologne and with Sandor Vegh in Salzburg. From 1998 till 2012 he was cellist of the Parkanyi Quartet (ex Orlando Quartet). In 2014 he became member of the ensemble LUDWIG. From autumn 2019 he is member of the Ruysdael Quartet.
Michael Muller regularly appears as chamber musician at many European festivals. (Edingburg festival,Holland Festival,Salzburger Festspiele,Aldeburgh festival)
He recorded celloconcertos by H. Andriessen,Georgi Minchev and Henk Badings. He plays on a cello by Januarius Gagliano (Napoli 1734), made available by the Dutch National Instrument Faoundation.